Carolina Panthers @ New Orleans Saints, Mercedes-Benz Superdome, 1:00 PM (Saints -10.5, O/U: 46.5)
Take the Saints to cover in the under, Saints 28-17.
Denver Broncos @ Buffalo Bills, New Era Field, 1:00 PM (Bills -4.5, O/: 37.5)
Take the Bills to cover in the over, Bills 24-17.
Detroit Lions @ Washington Redskins, FedEx Field, 1:00 PM (Redskins +4.5, O/U: 40.5)
Take the Lions to cover in the over, Lions 27-20.
Miami Dolphins @ Cleveland Browns, FirstEnergy Stadium, 1:00 PM (Browns -10.5, O/U: 45.5)
Take the Dolphins to cover in the loss, in the under, Browns 21-13.
New York Giants @ Chicago Bears, Soldier Field, 1:00 PM (Bears -6.5, O/U: 40.5)
Take the Giants to cover in the loss, in the under, Bears 20-17.
Oakland Raiders @ New York Jets, MetLife Stadium 1:00 PM (Jets +3.5, O/U: 45.5)
Take the Raiders to cover in the over, Raiders 28-20.
Pittsburgh Steelers @ Cincinnati Bengals, Paul Brown Stadium, 1:00 PM (Bengals +6.5, O/U: 37.5)
Take the Steelers to cover in the over, Steelers 23-13.
Tampa Bay Buccaneers @ Atlanta Falcons Mercedes-Benz Superdome, 1:00 PM (Falcons -3.5, O/U: 51.5)
Take the Falcons to cover in the over, Falcons 31-27.
Seattle Seahawks @ Philadelphia Eagles, Lincoln Financial Field, 1:00 PM (Eagles -1.5, O/U: 46.5)
Take the Seahawks to cover in the under, Seahawks 24-20.
Jacksonville Jaguars @ Tennessee Titans, Nissan Stadium, 4:05 PM (Titans -3.5, O/U: 41.5)
Take the Titans to cover in the under, Titans 21-17.
Dallas Cowboys @ New England Patriots, Gillette Stadium, 4:25 PM (Patriots -5.5, O/U: 44.5)
Take the Patriots to cover in the over, Patriots 31-24.
Green Bay Packers @ San Francisco 49ers, Levi’s Stadium, 8:20 PM (49ers -3.5, O/U: 47.5)
Take the Packers to cover in the over, Packers 27-24.
Colin Cowherd’s Blazin’ 5:
- Denver at Buffalo – Denver (+3.5)
- NY Giants at Chicago – NY Giants (+6)
- Oakland at NY Jets – Oakland (-3)
- Dallas at New England – Dallas (+6.5)
- Seattle at Philadelphia – Seattle (+1.5)