Arizona Cardinals @ Tampa Bay Buccaneers, Raymond James Stadium, 1:00 PM (Buccs -4.5, O/U: 52.5)
Take the Cardinals to cover in the win, in the under, Cardinals 24-20.
Atlanta Falcons @ New Orleans Saints, Mercedes-Benz Superdome, 1:00 PM (Saints -14, O/U: 51.5)
Take the Saints to cover in the over, Saints 31-16.
Baltimore Ravens @ Cincinnati Bengals, Paul Brown Stadium, 1:00 PM (Bengals +10, O/U: 44.5)
Take the Ravens to cover in the over, Ravens 35-17.
Buffalo Bills @ Cleveland Browns, FirstEnergy Stadium, 1:00 PM (Browns -3, O/U: 40.5)
Take the Bills to cover in the over, Bills 21-17.
Detroit Lions @ Chicago Bears, Soldier Field, 1:00 PM (Bears -4, O/U: 40.5)
Take the Bears to cover in the over, Bears 24-13.
Kansas City Chiefs @ Tennessee Titans, Nissan Stadium, 1:00 PM (Titans +6, O/U: 50.5)
Take the Chiefs to cover in the under, Chiefs 28-20.
New York Giants @ New York Jets, MetLife Stadium, 1:00 PM (Jets +3, O/U: 44.5)
Take the Jets to cover but the Giants to win, in the under, Giants 21-20.
Carolina Panthers @ Green Bay Packers, Lambeau Field, 1:00 PM (Packers -4.5, O/U: 47.5)
Take the Panthers to cover but the Packers to win, in the over, Packers 27-24.
Miami Dolphins @ Indianapolis Colts, Lucas Oil Stadium, 4:05 PM (Colts -10, O/U: 43.5)
Take the Dolphins to cover but the Colts to win, in the under, Colts 17-10.
Los Angeles Rams @ Pittsburgh Steelers, Heinz Field, 4:25 PM (Steelers +4.5, O/U: 43.5)
Take the Rams to cover in the over, Rams 28-17.
Minnesota Vikings @ Dallas Cowboys, AT&T Stadium, 8:20 PM, NBC (Cowboys -3.5, O/U: 49.5)
Take the Cowboys to cover in the over, Cowboys 28-24.
Colin Cowherd’s Blazin’ 5:
- Carolina at Green Bay – Carolina (+4.5)
- NY Giants at NY Jets – NY Jets (+3)
- Arizona at Tampa Bay – Arizona (+5)
- LA Rams at Pittsburgh – LA Rams (-4)
- Seattle at San Francisco – San Francisco (-6.5)