N.Y. Giants at Indianapolis, 1:00p, CBS (Colts -9.5, O/U: 48)
Take the Colts to cover in the under, Colts 24-10.
Jacksonville at Miami, 1:00p, CBS (Dolphins -3.5, O/U: 39)
Take the Dolphins to concert in the over, Dolphins 24-20.
Atlanta at Carolina, 1:00p FOX (Panthers +3, O/U: 45.5)
Take the Falcons to cover in the under, Falcons 24-16.
Buffalo at New England, 1:00p, CBS (Patriots -13.5, O/U: 45)
Take the Bills to cover in the loss, in the over, Patriots 28-20.
Cincinnati at Cleveland , 1:00p, CBS (Browns -10, O/U: 44)
Take the Bengals to cover in the loss, in the over, Browns 24-17.
Green Bay at N.Y. Jets , 1:00p, FOX (Jets +3, O/U: 47.5)
Take the Packers to cover in the over, Packers 31-24.
Houston at Philadelphia , 1:00p, CBS (Eagles -2, O/U: 47)
Take the Texans to cover in the win, in the over, Texans 31-20
Minnesota at Detroit , 1:00p, FOX (Lions +6.5, O/U: 43)
Take the Vikings to cover in the over, Vikings 28-21.
Tampa Bay at Dallas, 1:00p, FOX (Cowboys -7, O/U: 48)
Take the Cowboys to cover in the under, Cowboys 21-13.
Chicago at San Francisco, 4:05p, FOX (49ers +4.5, O/U: 44.5)
Take the Bears to cover in the under, Bears 24-17.
L.A. Rams at Arizona, 4:05p, FOX (Cardinals +14, O/U: 43.5)
Take the Rams to cover in the over, Rams 35-17.
Pittsburgh at New Orleans, 4:25p, CBS (Saints -6.5, O/U: 53.5)
Take the Saints to cover in the over, Saints 34-27.
Kansas City at Seattle, 8:20p, NBC (Seahawks +1.5, O/U: 55.5)
Take the Chiefs to cover in the over, Chiefs 31-28.
Colin Cowherd’s Blazin 5:
- Baltimore at LA Chargers – LA Chargers (-4.5)
- Green Bay at NY Jets – Green Bay (-3)
- Chicago at San Francisco – San Francisco (+4)
- NY Giants at Indianapolis – NY Giants (+9.5)
- Kansas City at Seattle – Seattle (+2.5)